- Link reaction and Kreb cycle -
Link reaction:
Pyruvate is oxidised to acetate // pyruvate loses a CO₂ and (X2) H // H is accepted by NAD to reduced NAD later used to produce ATP.
2-Carbon acetate combines coenzyme A (CoA) = acetylcoenzyme A
Krebs cycle
2-Carbon acetylcoenzyme A from link reaction combined with the 4-carbon molecule to produce a 6-carbon molecule.
6-Carbon molecule loses carbon dioxide and hydrogen to give 4-Carbon molecules and single molecule of ATP produced as result of substrate-level phosphorylation
4-Carbon molecule combines with new molecule of acetylcoenzyme A // cycle starts again.
Pyruvate, link reaction and krebs cycle produces
- Reduced coenzymes NAD and FAD // by oxidative phosphorylation potential to provide energy to produce ATP
- 1 ATP molecule
- 3 CO₂ molecules
2 Pyruvate molecules produced for each original glucose molecule.
Coenzymes = molecules that enzymes require to function, includes:
NAD - important throughout repsiration
FAD - important in the Kreb cycle
NADP - important in photosynthesis
Respiration NAD important carrier // works with dehydrogenase enzymes catalyse removal hydrogen atoms from substrates transfer them to the other molecules involved in oxidative phosphorylation.
Kreb cycle is important for:
Breaking down pyruvate into CO₂
Producing hydrogen atoms carried by NAD to electron transfer chain prodivde energy for oxidative phosphorylation = ATP produced
Regenerates 4 carbon molecule combines with acetylcoenzyme A
Source of intermediate compounds used by cells - fatty acids, amino acids and chlorophyll.
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